Two ladies discuss t-shirt slogans in an alleyway in Central Square in Cambridge, MA (near Boston). I took this shot to test the high ISO settings in low lighting on the Canon 40D. This was taken at 640 ISO and the sharpness was very nice compared with the XSi. I am pleased with this purchase already!
In case you were wondering, yes, that is Sarah Palin and Henry Louis Gates up there amongst the graffiti.
[Note: I did a poor job of framing this shot, I wish I got both their feet in the bottom part of the photo. I was too concerned with keeping my hands steady.]